Article
Mutations are involved in emergence of aminoglycoside-induced small colony variants of Staphylococcus aureus.
International journal of medical microbiology : IJMM - 1 Dec 2003
Schaaff Franziska, Bierbaum Gabriele, Baumert Nicole, Bartmann Peter, Sahl Hans-Georg
Abstract excerpt
Staphylococcus aureus small colony variants (SCVs) occur frequently after local treatment with aminoglycosides and cause persistent as well as recurrent infections. So far, the molecular mechanism of the emergence of SCVs is not understood and regulatory as well as genetic mechanisms seem conceiv...
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