Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotype switching is a natural consequence of Staphylococcus aureus replication.

Journal of bacteriology - 1 Oct 2012

Edwards Andrew M

Abstract excerpt

The pathogen Staphylococcus aureus undergoes phenotype switching in vivo from its normal colony phenotype (NCP) to a slow-growing, antibiotic-resistant small-colony-variant (SCV) phenotype that is associated with persistence in host cells and tissues. However, it is not clear whether phenotype switching is the result of a constitutive process that is selected for under certain conditions or is triggered by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptation, Physiological
Share to Bacteriological Techniques
Share to Cell Division

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Resistance, Bacterial

Share to Gentamicins

Share to Microbial Sensitivity Tests

Share to Staphylococcal Infections

Share to Staphylococcus aureus

Source

Open in PubMed Open full text

Identifiers

PMID: 22865841
DOI: 10.1128/JB.00948-12
PMCID: PMC3457229

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotype switching is a natural consequence of Staphylococcus aureus replication.PMID 22865841Read ↗

Staphylococcus aureus phenotype switching: an effective bacterial strategy to escape host immune response and establish a chronic infectionSemantic proximity Read ↗

Phenotypic switching of antibiotic resistance circumvents permanent costs in Staphylococcus aureus.Semantic proximity Read ↗

Unstable chromosome rearrangements in Staphylococcus aureus cause phenotype switching associated with persistent infectionsSemantic proximity Read ↗

The Complex Intracellular Lifecycle of Staphylococcus aureus Contributes to Reduced Antibiotic Efficacy and Persistent BacteremiaSemantic proximity Read ↗

The Complex Intracellular Lifecycle of Staphylococcus aureus Contributes to Reduced Antibiotic Efficacy and Persistent BacteremiaSemantic proximity Read ↗

Antibiotic activity against small-colony variants of Staphylococcus aureus: review of in vitro, animal and clinical data.Semantic proximity Read ↗

Small colony variants (SCVs) of Staphylococcus aureus--a bacterial survival strategy.Semantic proximity Read ↗

Clinical Significance and Pathogenesis of Staphylococcal Small Colony Variants in Persistent Infections.Semantic proximity Read ↗

Prolonged Growth of a Clinical Staphylococcus aureus Strain Selects for a Stable Small-Colony-Variant Cell TypeSemantic proximity Read ↗

Phenotypic and genetic changes in the life cycle of small colony variants of Salmonella enterica serotype Typhimurium induced by streptomycin.Semantic proximity Read ↗

Subpopulations in Strains of Staphylococcus aureus Provide Antibiotic ToleranceSemantic proximity Read ↗

An aroD Ochre Mutation Results in a Staphylococcus aureus Small Colony Variant That Can Undergo Phenotypic Switching via Two Alternative MechanismsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.