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Article

Neuropsychological functions in variant Alzheimer's disease with spastic paraparesis.

Journal of the neurological sciences - 15 Mar 2004

Verkkoniemi Auli, Ylikoski Raija, Rinne Juha O, Somer Mirja, Hietaharju Aki, Erkinjuntti Timo, Viitanen Matti, Kalimo Hannu, Haltia Matti

Abstract excerpt

Few data exist on the effects of specific Alzheimer's disease (AD)-related mutations on cognitive function. We present neuropsychological test results in eight members of a large kindred with variant Alzheimer's disease (VarAD) due to a deletion of the presenilin 1 (PS-1) gene, encompassing exon 9. The disease was neuropathologically characterized by the presence of large, unusual, "cotton wool" plaques (CWP)....

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Identifiers

PMID: 14759630
DOI: 10.1016/j.jns.2003.10.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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