Article
Selective activation of two sites in RNA by acridine-bearing oligonucleotides for clipping of designated RNA fragments.
Journal of the American Chemical Society - 11 Feb 2004
Kuzuya Akinori, Mizoguchi Ryo, Sasayama Takuro, Zhou Jing-Min, Komiyama Makoto
Abstract excerpt
Artificial enzymes for selective scission of RNA at two designated sites, which are valuable for advanced RNA science, have been prepared by combining lanthanide(III) ion with an oligonucleotide bearing two acridine groups. When these modified oligonucleotides form heteroduplexes with substrate R...
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