Article
The role of Toll-like receptors in combating mycobacteria.
Seminars in immunology - 1 Feb 2004
Krutzik Stephan R, Modlin Robert L
Abstract excerpt
In the battle against infections with mycobacteria, the body employs components of both the innate and adaptive arms of the immune system. Toll-like receptors (TLRs) mediate the activation of cells of the innate immune system leading to dynamic functions including direct anti-microbial activity, induction of cytokine secretion, triggering dendritic cell maturation, and triggering apoptosis. Furthermore, TLR...
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