Article
Two paired HPV-59 cervical cancer cell lines with distinct chemoradioresistant phenotypes.
Scientific reports - 4 Feb 2026
Tatarnikova Irina, Talyshev Vadim, Sen'kova Aleksandra, Markov Oleg, Mikhailova Darya, Pashkovskaya Oksana, Krasilnikov Sergey, Samoilova Elena, Gainer Tatyana, Brener Evgeniy, Zenkova Marina, Logashenko Evgeniya
Abstract excerpt
Cervical cancer (CC) is the fourth most common cancer among women worldwide and a leading cause of cancer-related death. While immortalized cell lines like HeLa are widely used, they often lose characteristic features of the original tumor due to long-term cultivation. Primary cell cultures offer a more representative model, as they retain key features of the native tumor microenvironment. Here, we establish and...
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