Article
Dosage adjustment of ribavirin based on renal function in Japanese patients with chronic hepatitis C.
Therapeutic drug monitoring - 1 Feb 2004
Maeda Yorinobu, Kiribayashi Yoshie, Moriya Takashi, Maruhashi Akira, Omoda Kei, Funakoshi Sachiyo, Murakami Teruo, Takano Mikihisa
Abstract excerpt
The daily dose of ribavirin is currently determined based on body weight. In the present study, the authors examined factors influencing total plasma clearance (CL(total)) and the toxic level on red blood cells of ribavirin in such body weight-based dosage adjustment in Japanese chronic hepatitis...
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