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Article

Dosage adjustment of ribavirin based on renal function in Japanese patients with chronic hepatitis C.

Therapeutic drug monitoring - 1 Feb 2004

Maeda Yorinobu, Kiribayashi Yoshie, Moriya Takashi, Maruhashi Akira, Omoda Kei, Funakoshi Sachiyo, Murakami Teruo, Takano Mikihisa

Abstract excerpt

The daily dose of ribavirin is currently determined based on body weight. In the present study, the authors examined factors influencing total plasma clearance (CL(total)) and the toxic level on red blood cells of ribavirin in such body weight-based dosage adjustment in Japanese chronic hepatitis C patients (13 male and 6 female). Patients received ribavirin (600 or 800 mg/d) orally, depending on their body...

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Identifiers

PMID: 14749543
DOI: 10.1097/00007691-200402000-00004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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