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Article

Glecaprevir/pibrentasvir for patients with chronic hepatitis C virus infection and severe renal impairment.

Journal of viral hepatitis - 1 Jun 2020

Liu Chen-Hua, Yang Sheng-Shun, Peng Cheng-Yuan, Lin Woan-Tyy, Liu Chun-Jen, Su Tung-Hung, Tseng Tai-Chung, Chen Pei-Jer, Chen Ding-Shinn, Kao Jia-Horng

Abstract excerpt

Data are limited regarding the real-world effectiveness and safety of glecaprevir/pibrentasvir (GLE/PIB) in patients with chronic hepatitis C virus (HCV) infection and severe renal impairment (RI). We aimed to evaluate the performance of GLE/PIB in patients with chronic kidney disease (CKD) stage 4 or 5 in Taiwan. 108 chronic HCV patients with CKD stage 4 (n = 32) or 5 (n = 76) receiving GLE/PIB for 8-12 weeks...

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PMID: 31981264
DOI: 10.1111/jvh.13265

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