Article
Capn5 is expressed in a subset of T cells and is dispensable for development.
Molecular and cellular biology - 1 Feb 2004
Franz Tanna, Winckler Lara, Boehm Thomas, Dear T Neil
Abstract excerpt
The Capn5 gene was inactivated by homologous recombination in ES cells that subsequently colonized the germ line of mice. The targeted mutation integrated a lacZ expression cassette into the Capn5 gene, allowing the expression of Capn5 mRNA to be examined in detail in heterozygous animals. Expression was observed in embryonic and newborn thymuses, in various epithelial tissues, and in tissues of the central...
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