Article
Haplotypic analyses of the IGF2-INS-TH gene cluster in relation to cardiovascular risk traits.
Human molecular genetics - 1 Apr 2004
Rodríguez Santiago, Gaunt Tom R, O'Dell Sandra D, Chen Xiao-He, Gu Dongfeng, Hawe Emma, Miller George J, Humphries Stephen E, Day Ian N M
Abstract excerpt
The IGF2-INS-TH genomic region has been implicated in various common disorders including the metabolic syndrome, type 2 diabetes and coronary heart disease (CHD). Here we present detailed haplotype analysis of 2743 males 51-62 years old in relation to body weight and composition, blood pressure (BP) and plasma triglycerides (TG). Use of the total data set was complicated by the number of loci typed, missing data,...
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