Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Methionine synthase D919G polymorphism, folate metabolism, and colorectal adenoma risk.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2004

Goode Ellen L, Potter John D, Bigler Jeannette, Ulrich Cornelia M

Abstract excerpt

Methionine synthase [5-methyltetrahydrofolate-homocysteine S-methyltransferase (MTR)] is involved in folate-mediated one-carbon metabolism, a pathway known to play a role in colorectal carcinogenesis. We investigated whether the MTR D919G polymorphism was associated with risk of colorectal adenoma in a colonoscopy-based study of 513 cases and 609 controls from Minneapolis, MN. Adenoma risk appeared...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
Share to Adenoma

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Colorectal Neoplasms

Share to Folic Acid

Share to Logistic Models

Share to Minnesota

Share to Sex Distribution

Source

Identifiers

PMID: 14744749
DOI: 10.1158/1055-9965.epi-03-0097

Genes

MTR
MTHFR
TYMS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Methionine synthase D919G polymorphism, folate metabolism, and colorectal adenoma risk.PMID 14744749Read ↗

Colorectal adenomas and the C677T MTHFR polymorphism: evidence for gene-environment interaction?Semantic proximity Read ↗

Methionine synthase and thymidylate synthase gene polymorphisms and colorectal adenoma risk: the self defense forces study.Semantic proximity Read ↗

Methylene tetrahydrofolate reductase genotype modifies the chemopreventive effect of folate in colorectal adenoma, but not colorectal cancer.Semantic proximity Read ↗

Thymidylate synthase polymorphisms, folate and B-vitamin intake, and risk of colorectal adenoma.Semantic proximity Read ↗

Genetic polymorphisms of methylenetetrahydrofolate reductase and colorectal cancer and adenoma.Semantic proximity Read ↗

Folate-genetics and colorectal neoplasia: what we know and need to know next.Semantic proximity Read ↗

Folate-related nutrients, genetic polymorphisms, and colorectal cancer risk: the fukuoka colorectal cancer study.Semantic proximity Read ↗

The methylenetetrahydrofolate reductase 677C-->T polymorphism and distal colorectal adenoma risk.Semantic proximity Read ↗

Polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene, intakes of folate and related B vitamins and colorectal cancer: a case-control study in a population with relatively low folate intake.Semantic proximity Read ↗

DNA methyltransferase and alcohol dehydrogenase: gene-nutrient interactions in relation to risk of colorectal polyps.Semantic proximity Read ↗

The polymorphisms in methylenetetrahydrofolate reductase, methionine synthase, methionine synthase reductase, and the risk of colorectal cancer.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.