Article
Calcium signaling is involved in dynein-dependent microtubule organization.
Molecular biology of the cell - 1 Apr 2004
Adamíková L'ubica, Straube Anne, Schulz Irene, Steinberg Gero
Abstract excerpt
The microtubule cytoskeleton supports cellular morphogenesis and polar growth, but the underlying mechanisms are not understood. In a screen for morphology mutants defective in microtubule organization in the fungus Ustilago maydis, we identified eca1 that encodes a sarcoplasmic/endoplasmic calcium ATPase. Eca1 resides in the endoplasmic reticulum and restores growth of a yeast mutant defective in calcium...
Topics
- Actins
- Calcium
- Calcium-Transporting ATPases
- Cell Nucleus
- Cytoskeleton
- Cytosol
- Dyneins
- Endoplasmic Reticulum
- Genotype
- Microtubules
- Models, Biological
- Mutation
- Myosin Type V
- Sarcoplasmic Reticulum Calcium-Transporting ATPases
- Signal Transduction
- Temperature
- Ustilago
