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Article

E69K mutation in β-tubulin 2 blocks cell wall integrity signaling during plant cell elongation.

EMBO reports - 1 Nov 2025

Yang Huanhuan, Wang Jie, Wang Guangda, Wang Chaofeng, Zhang Xiaxia, Tian Juan, Yu Yanjun, Kong Zhaosheng

Abstract excerpt

The intact cell wall is the prerequisite for plant cell morphogenesis. Loss of function in FRA1/KINESIN-4A, which encodes a microtubule-based kinesin motor, causes dwarfed growth phenotypes with reduced cell wall mechanics. However, the underlying mechanisms remain elusive. Here, using genetic screening, we identify a suppressor of fra1 (sofa1) mutation that specifically suppresses the dwarf phenotype of the fra1...

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Identifiers

PMID: 41028596
DOI: 10.1038/s44319-025-00507-4
PMCID: PMC12592460

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