Article
A split motor domain in a cytoplasmic dynein.
The EMBO journal - 17 Sept 2001
Straube A, Enard W, Berner A, Wedlich-Söldner R, Kahmann R, Steinberg G
Abstract excerpt
The heavy chain of dynein forms a globular motor domain that tightly couples the ATP-cleavage region and the microtubule-binding site to transform chemical energy into motion along the cytoskeleton. Here we show that, in the fungus Ustilago maydis, two genes, dyn1 and dyn2, encode the dynein heavy chain. The putative ATPase region is provided by dyn1, while dyn2 includes the predicted microtubule-binding site....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.