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Tissue-resident memory T cells contribute to protection against heterologous SARS-CoV-2 challenge

15 Oct 2024

Abstract excerpt

New vaccine formulations are based on circulating strains of virus, which have tended to evolve to more readily transmit human to human and to evade the neutralizing antibody response. An assumption of this approach is that ancestral strains of virus will not recur. Recurrence of these strains could be a problem for individuals not previously exposed to ancestral spike protein. Here, we addressed this by...

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PMID: 39405115
DOI: 10.1172/jci.insight.184074

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