Article
Influenza virosomes enhance class I restricted CTL induction through CD4+ T cell activation.
Vaccine - 26 Jan 2004
Schumacher Reto, Adamina Michel, Zurbriggen Rinaldo, Bolli Martin, Padovan Elisabetta, Zajac Paul, Heberer Michael, Spagnoli Giulio C
Abstract excerpt
Immunopotentiating reconstituted influenza virosomes (IRIV) are one of the few adjuvants currently licensed for human use. While their adjuvant capacity in the induction of humoral responses is clearly documented, few data exist on their effects on T cell immune response. Here we addressed IRIV adjuvance in the induction of HLA class I restricted cytotoxic T lymphocytes (CTL) in vitro. Lymphocyte stimulation with...
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