Article
Selection on codon usage in Drosophila americana.
Current biology : CB - 20 Jan 2004
Maside Xulio, Lee Angela Weishan, Charlesworth Brian
Abstract excerpt
Synonymous codons are not used at random, significantly influencing the base composition of the genome. The selection-mutation-drift model proposes that this bias reflects natural selection in favor of a subset of preferred codons. Previous estimates in Drosophila of the intensity of selective forces involved seem too large to be reconciled with theoretical predictions of the level of codon bias. This probably...
Topics
- Animals
- Base Composition
- Codon
- Databases, Nucleic Acid
- Drosophila
- Gene Conversion
- Models, Biological
- Mutation
- Polymorphism, Genetic
- Selection, Genetic