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Article

A Role for Thyroid Hormone in Wound Healing through Keratin Gene Expression

27 Jan 2004

Abstract excerpt

The importance of thyroid hormone (TH) in wound healing is not well understood. To gain insight, we evaluated the impact of TH deficiency on wound-healing genes in cultured keratinocytes. By RT-PCR, keratin 6a (K6a) and 16 (K16) gene expression in TH replete cells was 3.8- (P < 0.005) and 1.9-fold (P < 0.05) greater, respectively, than expression in TH-deficient cells. By real-time PCR, TH replete cell expression...

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PMID: 14736740
DOI: 10.1210/en.2003-1696

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