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Article

Age-dependent prognostic effects of genetic alterations in glioblastoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jan 2004

Batchelor Tracy T, Betensky Rebecca A, Esposito J Matthew, Pham Loc-Duyen D, Dorfman Molly V, Piscatelli Nicole, Jhung Sarah, Rhee David, Louis David N

Abstract excerpt

PURPOSE: Although the genetic alterations in glioblastoma have been well characterized, reports regarding their prognostic effects have been inconsistent. EXPERIMENTAL DESIGN: In this series of 140 consecutive cases of glioblastoma treated at a single center, we analyzed the frequency, age dependency and prognostic effects of TP53 mutation, CDKN2A/p16 deletion, EGFR amplification, as well as loss of chromosome...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14734474
DOI: 10.1158/1078-0432.ccr-0841-3

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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