Article
RNA folding affects the recruitment of SR proteins by mouse and human polypurinic enhancer elements in the fibronectin EDA exon.
Molecular and cellular biology - 1 Feb 2004
Buratti Emanuele, Muro Andrés F, Giombi Maurizio, Gherbassi Daniel, Iaconcig Alessandra, Baralle Francisco E
Abstract excerpt
In humans, inclusion or exclusion of the fibronectin EDA exon is mainly regulated by a polypurinic enhancer element (exonic splicing enhancer [ESE]) and a nearby silencer element (exonic splicing silencer [ESS]). While human and mouse ESEs behave identically, mutations introduced into the homolog...
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