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Article

The tumor suppressor p53 inhibits Net, an effector of Ras/extracellular signal-regulated kinase signaling.

Molecular and cellular biology - 1 Feb 2004

Nakade Koji, Zheng Hong, Ganguli Gitali, Buchwalter Gilles, Gross Christian, Wasylyk Bohdan

Abstract excerpt

The tumor suppressor function of p53 is linked to its ability to repress gene expression, but the mechanisms of specific gene repression are poorly understood. We report that wild-type p53 inhibits an effector of the Ras oncogene/mitogen-activated protein (MAP) kinase pathway, the transcription f...

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Identifiers

PMID: 14729959
DOI: 10.1128/MCB.24.3.1132-1142.2004
PMCID: PMC321436

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14729959-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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