Article
Comparative mapping of rat Iddm4 to segments on HSA7 and MMU6.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 2004
Hornum Lars, DeScipio Cheryl, Markholst Helle, Troutman Scott A, Novak Stephen, Leif Jean, Greiner Dale, Mordes John P, Blankenhorn Elizabeth P
Abstract excerpt
Iddm4 is one of several susceptibility genes that have been identified in the BB rat model of type 1 diabetes. The BB rat allele of this gene confers dominant predisposition to diabetes induction by immune perturbation in both the diabetes-prone and the diabetes-resistant substrains, whereas the...
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