Article
Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression.
American journal of respiratory and critical care medicine - 1 May 2004
Woodruff Prescott G, Dolganov Gregory M, Ferrando Ronald E, Donnelly Samantha, Hays Steven R, Solberg Owen D, Carter Roderick, Wong Hofer H, Cadbury Peggy S, Fahy John V
Abstract excerpt
Bronchial hyperresponsiveness in mild to moderate asthma may result from airway smooth muscle cell proliferation or acquisition of a hypercontractile phenotype. Because these cells have not been well characterized in mild to moderate asthma, we examined the morphometric and gene expression charac...
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