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Article

Identification of a novel NF-kappaB-binding site with regulation of the murine alpha2(I) collagen promoter.

The Journal of biological chemistry - 9 Apr 2004

Novitskiy Gennadiy, Potter James J, Rennie-Tankersley Lynda, Mezey Esteban

Abstract excerpt

Hepatic fibrosis is due to the increased synthesis and deposition of type I collagen. Acetaldehyde activates type I collagen promoters. Nuclear factor kappaB (NF-kappaB) was previously shown to inhibit expression of murine alpha(1)(I) and human alpha(2)(I) collagen promoters. The present study id...

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Source

Identifiers

PMID: 14722113
DOI: 10.1074/jbc.M311499200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14722113-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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