Article
[Polymorphism of MAO-B gene and NAD(P)H: quinone oxidoreductase gene in Parkinson's disease].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Apr 2001
Shao M, Liu Z, Tao E, Chen B
Abstract excerpt
OBJECTIVE: To investigate whether Parkinson's disease(PD) is associated with genetic polymorphism of intron 13 of monoamine oxidase B(MAO-B) and NAD(P)H: quinone oxidoreductase(NQO1) gene cDNA 609C to T. METHODS: Association study was performed in 126 PD patients and 136 healthy control subjects matched for age, sex and origin. The NQO1 gene polymorphism was analyzed with the polymerase chain reaction-restriction...
Topics
- Aged
- Alleles
- Female
- Humans
- Male
- Middle Aged
- Monoamine Oxidase
- Parkinson Disease
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Quinone Reductases
