Article
In vivo alteration of the keratin 17 gene in hair follicles by oligonucleotide-directed gene targeting.
Experimental dermatology - 1 Dec 2003
Fan W, Yoon K
Abstract excerpt
Using intradermal injection of a chimeric RNA-DNA oligonucleotide (RDO) or a single-stranded oligonucleotide (ssODN) into murine skin, we attempted to make a dominant mutation (R94p) in the conserve alpha-helical domain of keratin 17 (K17), the same mutation found in pachyononychia congenichia ty...
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