Article
Allelic variation at the VHa locus in natural populations of rabbit (Oryctolagus cuniculus, L.).
Journal of immunology (Baltimore, Md. : 1950) - 15 Jan 2004
Esteves Pedro J, Lanning Dennis, Ferrand Nuno, Knight Katherine L, Zhai Shi-Kang, van der Loo Wessel
Abstract excerpt
The large interallelic distances between the three rabbit Ig V(H)a lineages, a1, a2 and a3, suggest that the persistence time of the V(H)a polymorphism could amount to 50 million years, which is much longer than that of MHC polymorphisms. Rabbit originated in the Iberian Peninsula where two subspecies coexist, one of which is confined to Southwestern Iberia (Oryctolagus cuniculus algirus). We studied the V(H)...
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