Article
Physiological characterization of Haemophilus influenzae Rd deficient in its glutathione-dependent peroxidase PGdx.
The Journal of biological chemistry - 26 Mar 2004
Pauwels Frederik, Vergauwen Bjorn, Van Beeumen Jozef J
Abstract excerpt
The chimeric peroxidase PGdx of Haemophilus influenzae Rd belongs to a recently identified family of thiol peroxidases capable of reducing hydrogen peroxide as well as alkylhydroperoxides by means of glutathione redox cycling. In the present study, we constructed a H. influenzae Rd strain, deficient in its PGdx encoding gene (open reading frame HI0572). The mutant was shown by disk inhibition and liquid culture...
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