Article
Strong association of HLA class II sequences in Mexicans with Vogt-Koyanagi-Harada's disease.
Human immunology - 1 Sept 1999
Alaez C, del Pilar Mora M, Arellanes L, Cano S, Perez-Luque E, Vazquez M N, Olivo A, Burguete A, Hernandez A, Pedroza M, Gorodezky C
Abstract excerpt
Vogt-Koyanagi-Harada's syndrome (VKH) is an autoimmune disease prevalent in Mongoloids with evident participation of HLA. The aim of this study was to identify the class II DNA sequences involved in the etiopathogenesis of VKH in Mexican Mestizos. This study included 46 VKH patients and 170 controls. 75% were females (mean age at onset of 33.5 years). The disease evolved to chronicity (68%) and 25% of the...
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