Article
Selective expansion of V delta 1 + T cells from leprosy skin lesions.
The Journal of investigative dermatology - 1 Dec 1992
Uyemura K, Ho C T, Ohmen J D, Rea T H, Modlin R L
Abstract excerpt
T cells bearing gamma delta T-cell receptors (TCRs) are prominent residents of murine epidermis and appear to be important participants in the immune response to infection in human skin. The Mitsuda reaction in leprosy, induced by intradermal challenge with Mycobacterium leprae, provides an opportunity to study the cellular events that mediate a form of delayed-type hypersensitivity (DTH) in skin. T cells bearing...
Topics
- Amino Acid Sequence
- Bacterial Vaccines
- Base Sequence
- Cell Line
- Gene Rearrangement, T-Lymphocyte
- Humans
- Intradermal Tests
- Leprosy, Tuberculoid
- Molecular Sequence Data
- Mycobacterium leprae
- Phenotype