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Article

Hereditary nonpolyposis colorectal carcinoma (HNPCC) and HNPCC-like families: Problems in diagnosis, surveillance, and management.

Cancer - 1 Jan 2004

Lynch Henry T, Riley Bronson D, Weissman Scott M, Coronel Stephanie M, Kinarsky Yulia, Lynch Jane F, Shaw Trudy G, Rubinstein Wendy S, Weismann Scott

Abstract excerpt

BACKGROUND: To the authors' knowledge, hereditary nonpolyposis colorectal carcinoma (HNPCC) is the most commonly occurring hereditary disorder that predisposes to colorectal carcinoma (CRC), accounting for approximately 2-7% of all CRC cases diagnosed in the U.S each year. Its diagnosis is wholly dependent on a meticulously obtained family history of cancer of all anatomic sites, with particular attention to the...

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PMID: 14692024
DOI: 10.1002/cncr.11912

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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