Article
Calcineurin function is required for myofilament formation and troponin I isoform transition in Drosophila indirect flight muscle.
Developmental biology - 1 Jan 2006
Gajewski Kathleen M, Wang Jianbo, Schulz Robert A
Abstract excerpt
Mutations in the Drosophila calcineurin B2 gene cause the collapse of indirect flight muscles during mid stages of pupal development. Examination of cell fate-specific markers indicates that unlike mutations in genes such as vestigial, calcineurin B2 does not cause a shift in cell fate from indirect flight muscle to direct flight muscle. Genetic and molecular analyses indicate a severe reduction of myosin heavy...
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