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Article

Dynamic Changes in EPCAM Expression during Spermatogonial Stem Cell Differentiation in the Mouse Testis

15 Aug 2011

Abstract excerpt

BACKGROUND: Spermatogonial stem cells (SSCs) have the unique ability to undergo self-renewal division. However, these cells are morphologically indistinguishable from committed spermatogonia, which have limited mitotic activity. To establish a system for SSC purification, we analyzed the expression of SSC markers CD9 and epithelial cell adhesion molecule (EPCAM), both of which are also expressed on embryonic stem...

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PMID: 21858196
DOI: 10.1371/journal.pone.0023663

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