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[Cloning and identification of the priming glycosyltransferase gene involved in exopolysaccharide 139A biosynthesis in Streptomyces].

Yi chuan xue bao = Acta genetica Sinica - 1 Aug 2003

Wang Ling-Yan, Li Shi-Tao, Guo Lian-Hong, Jiang Rong, Li Yuan

Abstract excerpt

Recently in our laboratory, Streptomyces sp. 139 has been identified to produce a new exopolysaccharide designated EPS 139A that shows anti-rheumatic arthritis activity. The strategy of studying EPS 139A biosynthesis is to clone the key gene in the EPS biosynthesis pathway, i.e. the priming glycosyltransferase gene catalyzing the first step of nucleotide sugar transfer. Degenerate primers-based PCR approach was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 14682240

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