Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enzymatically synthesized exopolysaccharide of a probiotic strain Leuconostoc mesenteroides NTM048 shows adjuvant activity to promote IgA antibody responses.

Gut microbes - 1 Jan 2000

Matsuzaki Chiaki, Nakashima Yukari, Endo Ikuto, Tomabechi Yusuke, Higashimura Yasuki, Itonori Saki, Hosomi Koji, Kunisawa Jun, Yamamoto Kenji, Hisa Keiko

Abstract excerpt

Leuconostoc mesenteroides strain NTM048 produces an exopolysaccharide (EPS; glucose polymers 94% and fructose polymers 6%) with adjuvanticity for mucosal vaccination. Strain NTM048 includes three putative EPS-synthesizing genes, gtf1 and gtf2 for synthesizing glucose polymers, and lvnS for synthesizing fructose polymer. To elucidate the key polymer structure for adjuvanticity, two genes, gtf1 and gtf2, which were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibody Formation
Share to Bacterial Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Models, Animal

Share to Genetic Variation

Share to Immunoglobulin A

Share to Polysaccharides

Share to Probiotics

Source

Open in PubMed Open full text

Identifiers

PMID: 34288820
DOI: 10.1080/19490976.2021.1949097
PMCID: PMC8550178

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enzymatically synthesized exopolysaccharide of a probiotic strain Leuconostoc mesenteroides NTM048 shows adjuvant activity to promote IgA antibody responses.PMID 34288820Read ↗

Structural analysis and characterization of dextran produced by wild and mutant strains of Leuconostoc mesenteroides.Semantic proximity Read ↗

A low-cost recombinant glycoconjugate vaccine confers immunogenicity and protection against enterotoxigenic Escherichia coli infections in miceSemantic proximity Read ↗

Safety and Immunogenicity of a Candidate Bioconjugate Vaccine against Shigella flexneri 2a Administered to Healthy Adults: a Single-Blind, Randomized Phase I StudySemantic proximity Read ↗

Structural, genomic and phenotypic analysis of exopolysaccharide produced by Streptococcus thermophilus ST65.Semantic proximity Read ↗

Structure and biosynthesis of two exopolysaccharides produced by Lactobacillus johnsonii FI9785.Semantic proximity Read ↗

Development in the Concept of Bacterial Polysaccharide Repeating Unit-Based Antibacterial Conjugate VaccinesSemantic proximity Read ↗

Purification, Preliminary Structure and Antitumor Activity of Exopolysaccharide Produced by Streptococcus thermophilus CH9Semantic proximity Read ↗

Antibodies Targeting a Conserved Surface Polysaccharide Are Protective Against a Wide Range of Microbial Pathogens Producing β-1–6-Linked Poly-N-Acetylglucosamine (PNAG)Semantic proximity Read ↗

Generation of structurally diverse pectin oligosaccharides having prebiotic attributesSemantic proximity Read ↗

Development of a novel glycoengineering platform for the rapid production of conjugate vaccinesSemantic proximity Read ↗

Immunoregulatory effects on Caco-2 cells and mice of exopolysaccharides isolated from Lactobacillus acidophilus NCFMSemantic proximity Read ↗

Functional analysis of glycosyltransferase genes from Lactococcus lactis and other gram-positive cocci: complementation, expression, and diversity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.