Article
Differential export requirements for shuttling serine/arginine-type mRNA-binding proteins.
The Journal of biological chemistry - 13 Feb 2004
Häcker Sabine, Krebber Heike
Abstract excerpt
Messenger RNAs are transported to the cytoplasm bound to several shuttling mRNA-binding proteins. Here, we present the characterization of Hrb1, a novel component of the transported ribonucleoprotein complex in Saccharomyces cerevisiae. The protein is similar to the other two serine/arginine (SR)-type proteins in yeast, Gbp2 and Npl3. Hrb1 is nuclear at steady state and its import is mediated by the karyopherin...
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