Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alterations in HIV-1 LTR promoter activity during AIDS progression.

Virology - 5 Dec 2003

Hiebenthal-Millow Kirsten, Greenough Thomas C, Bretttler Doreen B, Schindler Michael, Wildum Steffen, Sullivan John L, Kirchhoff Frank

Abstract excerpt

HIV-1 variants evolving in AIDS patients frequently show increased replicative capacity compared to those present during early asymptomatic infection. It is known that late stage HIV-1 variants often show an expanded coreceptor tropism and altered Nef function. In the present study we investigated whether enhanced HIV-1 LTR promoter activity might also evolve during disease progression. Our results demonstrate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease Progression
Share to HIV-1
Share to HIV Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Long Terminal Repeat

Share to Jurkat Cells

Share to Leukocytes, Mononuclear

Share to Promoter Regions, Genetic

Share to U937 Cells

Source

Identifiers

PMID: 14675629
DOI: 10.1016/j.virol.2003.08.034

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alterations in HIV-1 LTR promoter activity during AIDS progression.PMID 14675629Read ↗

Genetic variation of the HIV-1 subtype C transmitted/founder viruses long terminal repeat elements and the impact on transcription activation potential and clinical disease outcomesSemantic proximity Read ↗

Genetic variation of the HIV-1 subtype C transmitted/founder viruses long terminal repeat elements and the impact on transcription activation potential and clinical disease outcomes.Semantic proximity Read ↗

Human immunodeficiency virus type-1 transcription: role of the 5'-untranslated leader region (review).Semantic proximity Read ↗

Divergent transcriptional regulation among expanding human immunodeficiency virus type 1 subtypesSemantic proximity Read ↗

Genetic analysis of the long terminal repeat (LTR) promoter region in HIV-1-infected individuals with different rates of disease progression.Semantic proximity Read ↗

The evolution of regulatory elements in the emerging promoter variant strains of HIV-1Semantic proximity Read ↗

The Evolution of Regulatory Elements in the Emerging Promoter-Variant Strains of HIV-1 Subtype CSemantic proximity Read ↗

Human immunodeficiency virus type 1 long terminal repeat variants from 42 patients representing all stages of infection display a wide range of sequence polymorphism and transcription activitySemantic proximity Read ↗

An AP-1 Binding Site in the Enhancer/Core Element of the HIV-1 Promoter Controls the Ability of HIV-1 To Establish Latent InfectionSemantic proximity Read ↗

Genetic Variability of Long Terminal Repeat Region between HIV-2 Groups Impacts Transcriptional Activity.Semantic proximity Read ↗

A novel HIV-1 isolate containing alterations affecting the NF-kappa B element.Semantic proximity Read ↗

Impact of viral activators and epigenetic regulators on HIV-1 LTRs containing naturally occurring single nucleotide polymorphisms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.