Article
The significance of the mutated divalent metal transporter (DMT1) on iron transport into the Belgrade rat brain.
Journal of neurochemistry - 1 Jan 2004
Moos Torben, Morgan Evan H
Abstract excerpt
Brain iron transport and distributional pattern of divalent metal transporter I (DMT1) were studied in homozygous Belgrade rats (b/b) which suffer from a mutation in the DMT1 gene. In adult rats, brain uptake of transferrin-bound iron injected intravenously (i.v.) was significantly lower compared with that in heterozygous Belgrade (+/b) and Wistar rats, whereas transferrin uptake was identical. The difference in...
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