Article
A 193-amino acid fragment of the SARS coronavirus S protein efficiently binds angiotensin-converting enzyme 2.
The Journal of biological chemistry - 30 Jan 2004
Wong Swee Kee, Li Wenhui, Moore Michael J, Choe Hyeryun, Farzan Michael
Abstract excerpt
The coronavirus spike (S) protein mediates infection of receptor-expressing host cells and is a critical target for antiviral neutralizing antibodies. Angiotensin-converting enzyme 2 (ACE2) is a functional receptor for the coronavirus (severe acute respiratory syndrome (SARS)-CoV) that causes SAR...
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