Article
HLA associations in leprosy patients from Mumbai, India.
Leprosy review - 1 Mar 2004
Shankarkumar U
Abstract excerpt
Genetic predisposition to both disease susceptibility and to host immune response has been postulated. In India, about 64% of leprosy prevalence and 78% of new case detection of the worlds estimated 719,330 cases occur. Convincing results have been reported from studies on HLA class II association in leprosy. However data on HLA class I association are limited and inconsistent. The HLA A, B and C allele...
Topics
- Alleles
- Case-Control Studies
- Cohort Studies
- DNA, Bacterial
- Developing Countries
- Female
- Gene Expression Regulation
- Genetic Predisposition to Disease
- Histocompatibility Antigens Class II
- Humans
- India
- Leprosy
- Male
- Phenotype
- Polymerase Chain Reaction
- Probability
- Risk Assessment
- Rural Population
