Article
[Investigation of single nucleotide polymorphisms in the promoter region of mannan-binding lectin gene in a Han population from Guangdong].
Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA - 1 Nov 2003
Lü Cheng-wei, Chen Zheng-liang, Diao Zhi-hong, Wang Fang-yong
Abstract excerpt
OBJECTIVE: To investigate the single nucleotide polymorphisms (SNP) in the promoter region of mannan-binding lectin (MBL) gene in a Han population in Guangdong Province. METHODS: A total of 167 blood samples were obtained from this Han population to isolate the genomic DNA from the leucocytes. The polymorphism alleles -550(G/C, named H/L alleles), -220(G/C, X/Y alleles) and +4(C/Tr, P/Q alleles) in the promoter...
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