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Article

Observation and characterization of the interaction between a single immunoglobulin binding domain of protein L and two equivalents of human kappa light chains.

The Journal of biological chemistry - 5 Mar 2004

Housden Nicholas G, Harrison Steven, Housden Hazel R, Thomas Karen-Anne, Beckingham Jennifer A, Roberts Siân E, Bottomley Stephen P, Graille Marc, Stura Enrico, Gore Michael G

Abstract excerpt

Detailed stopped-flow studies in combination with site-directed mutagenesis, isothermal titration calorimetry data and x-ray crystallographic knowledge have revealed that the biphasic pre-equilibrium fluorescence changes reported for a single Ig-binding domain of protein L from Peptostreptococcus magnus binding to kappa light chain are due to the binding of the kappa light chain at two separate sites on the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 14668335
DOI: 10.1074/jbc.M312938200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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