Article
Distribution, functional expression, and genetic organization of Cif, a phage-encoded type III-secreted effector from enteropathogenic and enterohemorrhagic Escherichia coli.
Journal of bacteriology - 1 Jan 2008
Loukiadis Estelle, Nobe Rika, Herold Sylvia, Tramuta Clara, Ogura Yoshitoshi, Ooka Tadasuke, Morabito Stefano, Kérourédan Monique, Brugère Hubert, Schmidt Herbert, Hayashi Tetsuya, Oswald Eric
Abstract excerpt
Enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli (EHEC) inject effector proteins into host cells via a type III secretion system encoded by the locus of enterocyte effacement (LEE). One of these effectors is Cif, encoded outside the LEE by a lambdoid prophage. In this study, we demonstrated that the Cif-encoding prophage of EPEC strain E22 is inducible and produces infectious phage...
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