Toward new strategies to select young endometrial cancer patients for mismatch repair gene mutation analysis.

doi:10.1200/JCO.2003.04.094

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Article

Toward new strategies to select young endometrial cancer patients for mismatch repair gene mutation analysis.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Dec 2003

Berends Maran J W, Wu Ying, Sijmons Rolf H, van der Sluis Tineke, Ek Wietske Boersmavan, Ligtenberg Marjolijn J L, Arts Neeltje J W, ten Hoor Klaske A, Kleibeuker Jan H, de Vries Elisabeth G E, Mourits Marian J E, Hollema Harry, Buys Charles H C M, Hofstra Robert M W, van der Zee Ate G J

Abstract excerpt

PURPOSE: To determine the frequency of mismatch repair (MMR) gene germline mutations in endometrial cancer patients who were diagnosed at less than 50 years of age; to relate the presence of mutations to family history, histopathologic data, presence of tumor microsatellite instability (MSI), and immunostaining; and to formulate criteria for genetic testing in these patients. PATIENTS AND METHODS: Endometrial...

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Identifiers

PMID: 14645426
DOI: 10.1200/JCO.2003.04.094

Genes

MLH1
MSH2
MSH6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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