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Mismatch Repair Universal Screening of Endometrial Cancers (MUSE) in a Canadian Cohort

15 Jan 2021

Abstract excerpt

BACKGROUND: Approximately 2-6% of endometrial cancers (ECs) are due to Lynch Syndrome (LS), a cancer predisposition syndrome caused by germline pathogenic variants (PVs) affecting the DNA mismatch repair (MMR) pathway. Increasingly, universal tissue-based screening of ECs has been proposed as an efficient and cost-effective way to identify families with LS, though few studies have been published on Canadian...

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PMID: 33467402
DOI: 10.3390/curroncol28010052

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