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Article

Women With Synchronous Primary Cancers of the Endometrium and Ovary: Do They Have Lynch Syndrome?

17 Dec 2005

Abstract excerpt

PURPOSE: Lynch syndrome (hereditary nonpolyposis colorectal cancer; HNPCC) is an autosomal-dominant cancer predisposition syndrome that increases risk for multiple cancers, including colon, endometrial, and ovarian cancer. Revised Bethesda Criteria recommend that patients with two HNPCC-associated cancers undergo molecular evaluation to determine whether they have a mismatch repair (MMR) defect associated with...

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Identifiers

PMID: 16361634
DOI: 10.1200/jco.2005.03.5915

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