Article
Predicting the therapeutic response in patients with chronic hepatitis C: the role of viral kinetic studies.
The Journal of antimicrobial chemotherapy - 1 Jan 2004
Ferenci Peter
Abstract excerpt
A substantial proportion of patients infected with hepatitis C virus (HCV) genotype 1 still does not respond to pegylated interferon-alfa/ribavirin (IFN/RBV) therapy. Factors which identify potential non-responders are needed to limit exposure to drugs in patients unlikely to benefit from treatment and to save health care resources. Host predictive factors have a low negative predictive value. In contrast, viral...
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