Article
Prediction of treatment outcome in patients with chronic hepatitis C: significance of baseline parameters and viral dynamics during therapy.
Hepatology (Baltimore, Md.) - 1 Mar 2003
Berg Thomas, Sarrazin Christoph, Herrmann Eva, Hinrichsen Holger, Gerlach Tilman, Zachoval Reinhart, Wiedenmann Bertram, Hopf Uwe, Zeuzem Stefan
Abstract excerpt
In patients with chronic hepatitis C virus (HCV) infection scheduled for a 48-week treatment period, premature discontinuation of treatment was previously recommended if HCV-RNA levels remained detectable at week 24 of therapy. Considering the number of side effects and treatment costs, measurement of initial viral decline during therapy may identify virologic nonresponse earlier than 24 weeks. We retrospectively...
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