Article
Relationships among various nucleoside resistance-conferring mutations in the reverse transcriptase of HIV-1.
The Journal of antimicrobial chemotherapy - 1 Jan 2004
Turner Dan, Brenner Bluma, Wainberg Mark A
Abstract excerpt
Highly active antiretroviral therapy has significantly improved HIV-related morbidity and mortality, and nucleoside reverse transcriptase inhibitors remain an essential component of treatment. However, the emergence of HIV-1 mutated strains that are resistant to one or more antiretroviral drugs is a leading cause of treatment failure among patients living with HIV/AIDS. These resistant strains may often suffer...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
