Article
Identification of quorum-sensing regulated proteins in the opportunistic pathogen Pseudomonas aeruginosa by proteomics.
Environmental microbiology - 1 Dec 2003
Arevalo-Ferro Catalina, Hentzer Morten, Reil Gerold, Görg Angelika, Kjelleberg Staffan, Givskov Michael, Riedel Kathrin, Eberl Leo
Abstract excerpt
The Gram-negative bacterium Pseudomonas aeruginosa is an opportunistic human pathogen which is responsible for severe nosocomial infections in immunocompromised patients and is the major pathogen in cystic fibrosis. The bacterium utilizes two interrelated quorum-sensing (QS) systems, which rely on N-acyl-homoserine lactone (AHL) signal molecules, to control the expression of virulence factors and biofilm...
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